I have been using 7 1/2 game loads in a single shot twelve gauge, for many years. I have killed well over a hundred rabbits, in that time, and most fell on the spot or within a few feet. The small shot are very effective on both cottontails and swamp rabbits. I've had very little problem with too many shot in the meat. On very close shots, I aim at the tip of their nose and thus avoid blowing them apart. If I miss, I don't worry about it anyway. I used #4s and 6s years ago but, switched to the lighter loads when my son gave me some for Christmas one year. I ran short on ammo and decided to try the game loads and was pleasantly surprised at how effective they were. They are a lot easier on the shoulder with that old single shot also.